Franck Fieschi Selected Research

DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)

4/2022	Glycomimetic ligands block the interaction of SARS-CoV-2 spike protein with C-type lectin co-receptors.
10/2021	Low-Valent Calix[4]arene Glycoconjugates Based on Hydroxamic Acid Bearing Linkers as Potent Inhibitors in a Model of Ebola Virus Cis-Infection and HCMV-gB-Recombinant Glycoprotein Interaction with MDDC Cells by Blocking DC-SIGN.
1/2021	New lipophilic glycomimetic DC-SIGN ligands: Stereoselective synthesis and SPR-based binding inhibition assays.
6/2019	Correction to Unprecedented Thiacalixarene Fucoclusters as Strong Inhibitors of Ebola cis-Cell Infection and HCMV-gB Glycoprotein/DC-SIGN C-type Lectin Interaction.
1/2019	Unprecedented Thiacalixarene Fucoclusters as Strong Inhibitors of Ebola cis-Cell Infection and HCMV-gB Glycoprotein/DC-SIGN C-type Lectin Interaction.
1/2018	Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition.
1/2018	Fine Mapping the Interaction Between Dendritic Cell-Specific Intercellular Adhesion Molecule (ICAM)-3-Grabbing Nonintegrin and the Cytomegalovirus Envelope Glycoprotein B.
11/2016	Nonhydrolyzable C-disaccharides, a new class of DC-SIGN ligands.
1/2016	Solution Behavior of Amphiphilic Glycodendrimers with a Rod-Like Core.
3/2015	Designing nanomolar antagonists of DC-SIGN-mediated HIV infection: ligand presentation using molecular rods.

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Franck Fieschi Research Topics

Disease

26	Infections 04/2022 - 11/2002
8	Neoplasms (Cancer) 01/2022 - 09/2011
5	Virus Diseases (Viral Diseases) 01/2016 - 07/2003
5	HIV Infections (HIV Infection) 03/2015 - 03/2010
3	Inflammation (Inflammations) 10/2020 - 11/2011
3	Communicable Diseases (Infectious Diseases) 11/2011 - 05/2006
2	Atherosclerosis 06/2021 - 11/2011
2	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2021 - 09/2011
2	Autoimmune Diseases (Autoimmune Disease) 10/2020 - 10/2020
2	Melanoma (Melanoma, Malignant) 01/2020 - 01/2019
2	Chronic Granulomatous Disease 12/2014 - 10/2010
1	Carcinogenesis 01/2022
1	COVID-19 11/2021
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2021
1	Lupus Nephritis 11/2021
1	Diabetic Nephropathies (Diabetic Nephropathy) 06/2021
1	Fibrosis (Cirrhosis) 06/2021
1	Hypertension (High Blood Pressure) 06/2021
1	Schistosomiasis (Bilharziasis) 10/2020
1	Hypersensitivity (Allergy) 10/2020
1	Ataxia Telangiectasia (Louis Bar Syndrome) 12/2017
1	Dengue (Dengue Fever) 04/2014
1	Pathologic Processes 11/2011
1	Arthritis (Polyarthritis) 09/2011

Drug/Important Bio-Agent (IBA)

23	DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN)IBA 04/2022 - 11/2002
15	C-Type Lectins (C-Type Lectin)IBA 04/2022 - 05/2006
12	LigandsIBA 01/2021 - 05/2007
6	Polysaccharides (Glycans)IBA 04/2022 - 11/2011
6	Glycoproteins (Glycoprotein)IBA 04/2022 - 01/2019
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2011
4	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2019 - 04/2005
4	Antiviral Agents (Antivirals)IBA 11/2016 - 07/2007
3	CarbohydratesIBA 10/2020 - 07/2007
3	Pharmaceutical PreparationsIBA 10/2020 - 06/2014
3	AnionsIBA 01/2019 - 04/2005
3	Superoxides (Superoxide)IBA 01/2019 - 04/2005
3	LectinsIBA 07/2011 - 05/2007
3	IntegrinsIBA 03/2010 - 07/2003
2	GlycoconjugatesIBA 10/2021 - 05/2007
2	AntigensIBA 01/2020 - 01/2019
2	Biological ProductsIBA 01/2019 - 11/2011
2	cytochrome b558IBA 12/2017 - 12/2014
2	Dendrimers (Dendrons)IBA 02/2013 - 07/2011
2	dendronIBA 01/2012 - 03/2010
2	AntibodiesIBA 07/2003 - 11/2002
1	Carbohydrate Tumor-Associated Antigens (Antigens, Tumor-Associated Carbohydrate)IBA 01/2022
1	Tn antigenIBA 01/2022
1	Galactose (Galactopyranose)FDA LinkGeneric 01/2022
1	Amino Acids FDA Link 01/2022
1	AcetylgalactosamineIBA 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	Threonine (L-Threonine)FDA Link 01/2022
1	LipidsIBA 11/2021
1	CholesterolIBA 11/2021
1	HDL LipoproteinsIBA 11/2021
1	Biomarkers (Surrogate Marker)IBA 11/2021
1	calix(4)areneIBA 10/2021
1	Calixarenes (Calixarene)IBA 10/2021
1	AcidsIBA 10/2021
1	Hydroxamic Acids (Hydroxamic Acid)IBA 10/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 06/2021
1	MucinsIBA 10/2020
1	VaccinesIBA 10/2020
1	Carrier Proteins (Binding Protein)IBA 10/2020
1	Peptides (Polypeptides)IBA 01/2020
1	Conjugate VaccinesIBA 01/2019
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019
1	Toll-Like Receptor 7IBA 01/2019
1	MannosidesIBA 01/2019
1	Phosphotransferases (Kinase)IBA 12/2017
1	phorbolIBA 12/2017
1	ChemokinesIBA 01/2012
1	Cell Adhesion MoleculesIBA 01/2012
1	FucoseIBA 11/2011
1	ClusterinIBA 11/2011
1	celastrolIBA 09/2011
1	PolyestersIBA 07/2011
1	Intercellular Adhesion Molecule-3IBA 03/2010
1	DisaccharidesIBA 07/2007

Therapy/Procedure

1	Therapeutics 10/2020